CRISPR-Chip
  
The ultrasensitive graphene biosensor allowing assessment of the quality of your gRNAs for your CRISPR needs with a highly intuitive graphical user interface customized per application, commercial scalability, and build-in efficient signal and software analysis.

Reduce the time and costs necessary to take your CRISPR application from target identification to hybridization and cleavage.
  

  CRISPR QC

  DNA Search Engine

The CRISPR-Chip system optimizes guide RNA and Cas-variants for the highest binding efficiency and specificity for the preferred biology of interest.
Tool that identifies genomic regions of guide RNA binding, maps off-target locations and improves confidence in guide RNA localization to desired regions with minimal off-target binding.
​​Nanosens introduces the CRISPR-Chip - a technology invented by Dr. Kiana Aran while at Berkeley and KGI and then licensed out to Nanosens. Exclusive license partnership with the global leader of graphene biosensors, Cardea Inc., has opened the potential for CRISPR guide RNA optimization and target identification.

 ​​​Source: UC Berkeley News video of CRISPR-Chip​​
 
CRISPR-Chip offers two applications types to start with:

CRISPR QC: A quality control (QC) system for researchers doing gene-editing with CRISPR-cas9, by providing a deep and instant insight to what the CRISPR complex is doing while working its way through the genome. It can be applied for quality control via different ways; e.g. a way of optimizing for your guide RNAs and enabling you to select guide RNAs with high on-target efficiency and with no off-target cleavage. It can also help optimize development of new Cas-variance or simply picking the optimal variance to the different system biology challenges and sample types.

As a way to portray the future CRISPR-QC tool we are working on for now, please read the draft CRISPR-Chip Brochure below:
Read the Brochure
The DNA Search Engine: Imagine if you had to wait weeks for the result every time you used an online search engine... It would not really be the Internet as we know it. Something even more painful would be if the result you got back from your online search was "the WHOLE thing”, so you had to use a computer to go through it all to find the one page or part of your interest. We are thankful for having search engines helping us find information on the Internet, but we also need them for the Genomes. We and our co-development partner Cardea are therefore looking for partners to help us build products and an applications version of "the Biology Search Engine" that the CRISPR-chip technology allows us to create.

CRISPR-Chip is expected to be made commercially available and distributed via a larger life science organization(s).  Potential partnerships are currently being negotiated.

See our conceptual graphics we provide our potential commercial partners:​
CRISPR Dx Graphics

Early Access Partner Program

Be one of the first to try out the CRISPR-Chip and find new ways of applying this powerful sensor technology. We are currently seeking partners who want to do proof-of-product performance studies with different applications, provide valuable early feedback, and bring to market developed applications.
EAPP Form